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Literature summary for 3.4.22.51 extracted from

  • Ferrao, P.M.; dAvila-Levy, C.M.; Araujo-Jorge, T.C.; Degrave, W.M.; Goncalves, A.d.a. .S.; Garzoni, L.R.; Lima, A.P.; Feige, J.J.; Bailly, S.; Mendonca-Lima, L.; Waghabi, M.C.
    Cruzipain activates latent TGF-beta from host cells during T. cruzi invasion (2015), PLoS ONE, 10, e0124832 .
    View publication on PubMedView publication on EuropePMC
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Application

Application Comment Organism
medicine cruzipain inhibition is a chemotherapeutic approach for Chagas disease because of its trypanocidal activity and due to the inhibitory effect on TGF-beta activation Trypanosoma cruzi

Localization

Localization Comment Organism GeneOntology No. Textmining

Organism

Organism UniProt Comment Textmining
Trypanosoma cruzi P25779
-
-

Source Tissue

Source Tissue Comment Organism Textmining
epimastigote
-
 Trypanosoma cruzi
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